グリベック錠１００ｍｇ
基本情報
| 項目 | 値 |
|---|---|
| DrugBank ID | DB00619 |
| エビデンスレベル | L5（計算予測のみ） |
| 予測適応症数 | 100 |
| 日本商品名（例） | イマチニブメシル酸塩１００ｍｇ錠, イマチニブ錠１００ｍｇ「オーハラ」, イマチニブ錠１００ｍｇ「ケミファ」 |
承認適応症（KEGG）
慢性骨髄性白血病、消化管間質腫瘍 (KIT陽性)、急性リンパ性白血病 (フィラデルフィア染色体陽性)、好酸球増多症候群 (FIP1L1-PDGFRα陽性)、慢性好酸球性白血病 (FIP1L1-PDGFRα陽性)
予測適応症（TxGNN）
以下は TxGNN モデルにより予測された潜在的新適応症です。スコアが高いほど関連性が高いと予測されています。
| # | 適応症 | スコア | ソース |
|---|---|---|---|
| 1 | dermatofibrosarcoma protuberans | 99% | DL |
| 2 | heart fibrosarcoma | 99% | DL |
| 3 | fibroblastic neoplasm | 99% | DL |
| 4 | conventional fibrosarcoma | 99% | DL |
| 5 | kidney fibrosarcoma | 99% | DL |
| 6 | low grade fibromyxoid sarcoma | 99% | DL |
| 7 | liposarcoma | 99% | DL |
| 8 | liver fibrosarcoma | 99% | DL |
| 9 | autosomal recessive familial Mediterranean fever | 99% | DL |
| 10 | ovarian myxoid liposarcoma | 99% | DL |
| 11 | familial rhabdoid tumor | 99% | DL |
| 12 | benign PEComa | 99% | DL |
| 13 | uterine corpus perivascular epithelioid cell tumor | 99% | DL |
| 14 | lymphangiomyoma | 99% | DL |
| 15 | lymphangioleiomyomatosis | 99% | DL |
| 16 | bone fibrosarcoma | 99% | DL |
| 17 | cutaneous undifferentiated pleomorphic sarcoma | 99% | DL |
| 18 | cutaneous leiomyosarcoma (disease) | 99% | DL |
| 19 | central nervous system fibrosarcoma | 99% | DL |
| 20 | vulva sarcoma | 99% | DL |
| 21 | gallbladder leiomyosarcoma | 99% | DL |
| 22 | lung PEComa | 99% | DL |
| 23 | breast fibrosarcoma | 99% | DL |
| 24 | uterine corpus leiomyoma | 99% | DL |
| 25 | familial Mediterranean fever, autosomal dominant | 99% | DL |
| 26 | parameningeal embryonal rhabdomyosarcoma | 99% | DL |
| 27 | autoinflammatory syndrome with immune deficiency | 99% | DL |
| 28 | uterine corpus myxoid leiomyosarcoma | 99% | DL |
| 29 | botryoid-type embryonal rhabdomyosarcoma of the vagina | 99% | DL |
| 30 | leiomyosarcoma | 99% | DL |
| 31 | prostate embryonal rhabdomyosarcoma | 99% | DL |
| 32 | embryonal extrahepatic bile duct rhabdomyosarcoma | 99% | DL |
| 33 | extrahepatic bile duct rhabdomyosarcoma | 99% | DL |
| 34 | rhabdomyosarcoma (disease) | 99% | DL |
| 35 | mixed endometrial stromal and smooth muscle tumor | 99% | DL |
| 36 | uterine corpus epithelioid leiomyosarcoma | 99% | DL |
| 37 | anus leiomyosarcoma | 99% | DL |
| 38 | retroperitoneal sarcoma | 99% | DL |
| 39 | small intestinal sarcoma | 99% | DL |
| 40 | liver sarcoma | 99% | DL |
| 41 | myxofibrosarcoma | 99% | DL |
| 42 | mastocytosis | 98% | DL |
| 43 | familial Mediterranean fever | 98% | DL |
| 44 | situs inversus | 98% | DL |
| 45 | extracutaneous mastocytoma | 98% | DL |
| 46 | childhood malignant neoplasm | 98% | DL |
| 47 | aggressive systemic mastocytosis | 98% | DL |
| 48 | heart position anomaly | 98% | DL |
| 49 | basal ganglia calcification, idiopathic | 98% | DL |
| 50 | spindle cell liposarcoma | 98% | DL |
（上位50件を表示。全100件の予測があります）
免責事項
これらの予測は研究目的のみであり、医療アドバイスを構成するものではありません。 臨床応用には必ず適切な検証が必要です。