Methotrexate
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00563 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 24 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | spondyloarthropathy | TxGNN Knowledge Graph |
| 2 | B-cell neoplasm | TxGNN Knowledge Graph |
| 3 | granulomatous slack skin disease | TxGNN Knowledge Graph |
| 4 | female breast carcinoma | TxGNN Knowledge Graph |
| 5 | precursor T-cell acute lymphoblastic leukemia | TxGNN Knowledge Graph |
| 6 | bone osteosarcoma | TxGNN Knowledge Graph |
| 7 | primary cutaneous T-cell lymphoma | TxGNN Knowledge Graph |
| 8 | folliculotropic mycosis fungoides | TxGNN Knowledge Graph |
| 9 | leukemia, lymphocytic, susceptibility to | TxGNN Knowledge Graph |
| 10 | acute lymphoblastic leukemia (disease) | TxGNN Knowledge Graph |
| 11 | acute lymphoblastic/lymphocytic leukemia | TxGNN Knowledge Graph |
| 12 | Langerhans cell histiocytosis | TxGNN Knowledge Graph |
| 13 | lymphoma, non-Hodgkin, familial | TxGNN Knowledge Graph |
| 14 | juvenile arthritis due to defect in LACC1 | TxGNN Knowledge Graph |
| 15 | non-Hodgkin lymphoma | TxGNN Knowledge Graph |
| 16 | mycosis fungoides and variants | TxGNN Knowledge Graph |
| 17 | mantle cell lymphoma | TxGNN Knowledge Graph |
| 18 | juvenile idiopathic arthritis | TxGNN Knowledge Graph |
| 19 | gestational trophoblastic neoplasm | TxGNN Knowledge Graph |
| 20 | localized pagetoid reticulosis | TxGNN Knowledge Graph |
| 21 | upper aerodigestive tract neoplasm | TxGNN Knowledge Graph |
| 22 | lung neoplasm | TxGNN Knowledge Graph |
| 23 | lymphosarcoma | TxGNN Knowledge Graph |
| 24 | Burkitt lymphoma | TxGNN Knowledge Graph |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.